Within the RBC hypoxia stimulates glycolysis by which of the following regulating pathways ?

Hypoxia stimulates pyruvate dehydrogenase by increased, 2, 3DPG
Activation of the regulatory enzymes by high PH
Hypoxia stimulates release of all glycolytic enzymes from Band 3 on RBC membrane
Hypoxia inhibits hexokinase
Hypoxia stimulates release of all glycolytic enzymes from Band 3 on RBC membrane  

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